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  • Title: [Safety of low dose unfractionated heparin (LDUH) in patients undergoing hip fracture operation].
    Author: Arimune M, Morita H.
    Journal: Masui; 2008 Oct; 57(10):1223-6. PubMed ID: 18975536.
    Abstract:
    BACKGROUND: Japanese guideline for prevention of venous thromboemobolism recommends to use LDUH in high-risk patients. Femoral neck fracture belongs to high-risk group. However, use of LUDH has possibilities of causing a fresh hemorrhage from the fracture part and spinal hematoma due to spinal anesthesia. We investigated safety of LDUH in patients for hemiarthroplasty. METHODS: We compared group receiving LDUH (Group H) with group receiving nothing (Group N) and examined changes of hemoglobin concentrations, amount of perioperative hemorrhage and complications (e.g. spinal hematoma, massive surgical hemorrhage and thrombocytopenia). RESULTS: No significant differences were seen in two groups and no major complications occurred, except for occurrence of pulmonary embolism in Group N. CONCLUSIONS: We suggest that using LDUH in hip fracture surgery is safe.
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