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  • Title: Synthesis and in vitro evaluation of the antifungal activities of dihydropyrimidinones.
    Author: Singh OM, Singh SJ, Devi MB, Devi LN, Singh NI, Lee SG.
    Journal: Bioorg Med Chem Lett; 2008 Dec 15; 18(24):6462-7. PubMed ID: 18977139.
    Abstract:
    Copper (II) chloride in the absence of any solvent, efficiently catalyses the synthesis of dihydropyrimidinones (80-96% yields) by the Biginelli reaction. Six compounds were selected and examined their antifungal activities against the radial growth of three fungal species viz., Trichoderma hammatum, Trichoderma koningii and Aspergillus niger.
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