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  • Title: Implementing therapy with opioids in patients with cancer.
    Author: de Leon-Casasola O.
    Journal: Oncol Nurs Forum; 2008 Nov; 35 Suppl():7-12. PubMed ID: 18980934.
    Abstract:
    PURPOSE/OBJECTIVES: To review strategies to optimize the management of chronic pain in patients with cancer, with an emphasis on the role of opioid analgesics. DATA SOURCES: Published research, articles from a literature review, and U. S. statistics. DATA SYNTHESIS: Treatment for cancer pain remains suboptimal. With the therapies currently available, as much as 90% of cancer pain can be controlled. Opioid analgesics are an important component of pain management in patients with cancer. CONCLUSIONS: The management of cancer pain is a challenging endeavor that requires an understanding of the etiologies of cancer and the types of pain they can produce. Opioid analgesics are a mainstay of treatment for cancer pain. New drug formulations, delivery systems, and strategies, particularly opioid rotation, are available to optimize cancer pain management. IMPLICATIONS FOR NURSING: Opioid rotation may be useful for opening the therapeutic window and establishing a more advantageous analgesic-to-toxicity ratio in patients with cancer.
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