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  • Title: Origin of so-called mesothelioma of the atrioventricular node. An immunohistochemical study.
    Author: Monma N, Satodate R, Tashiro A, Segawa I.
    Journal: Arch Pathol Lab Med; 1991 Oct; 115(10):1026-9. PubMed ID: 1898229.
    Abstract:
    To determine the origin of a mesothelioma of the atrioventricular node, immunohistochemical studies that used various antibodies, including the antibody against mesothelial cells, were performed on a mesothelioma of the atrioventricular node in a case. The lining cells of the tubules that composed the tumor were negative when tested with anti-mesothelial cell antibodies. Carcinoembryonic antigen was negative, but the secretory component was positive. Serotonin and calcitonin were positive in a few cells. We concluded that a mesothelial origin was unlikely, and it was suggested that the tumor was of an entodermal origin.
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