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  • Title: Ruthenium polypyridyl peptide conjugates: membrane permeable probes for cellular imaging.
    Author: Neugebauer U, Pellegrin Y, Devocelle M, Forster RJ, Signac W, Moran N, Keyes TE.
    Journal: Chem Commun (Camb); 2008 Nov 14; (42):5307-9. PubMed ID: 18985192.
    Abstract:
    Two novel polyarginine labelled ruthenium polypyridyl dyes are reported, one conjugated to five, (Ru-Ahx-R5), and one to eight arginine residues, (Ru-Ahx-R8); both complexes exhibit long-lived, intense, and oxygen-sensitive luminescence; (Ru-R8) is passively, efficiently and very rapidly transported across the cell membrane into the cytoplasm without requirement for its permeablisation.
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