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  • Title: [Fractional composition of cytoplasmic RNP-particles in the cells of Zajdela ascitic hepatoma and the liver of a tumor-bearing animal].
    Author: Alekhina RP, Likhtenshteĭn AV, Shapot VS.
    Journal: Biull Eksp Biol Med; 1976; 82(11):1354-7. PubMed ID: 189856.
    Abstract:
    The relative content of poly(A)-RNA in the cytoplasm was greater in the cells of Zajdela hepatoma and the liver of tumour-bearing rats than in the normal hepatocytes of rats. Besides, the tumour cells (and to a lesser extent the hepatocytes of the tumour-bearing animal) were characterized by the changes in the ratio of the polyribosomes and monoribosomes usual for normal hepatocytes (and correspondingly between the m-RNP-particles and the informosomes) in favour of the latter, this pointing to definite changes in their protein-synthesizing apparatus. As judged by some of the parameters, the cells of the tumour-bearing by some of the parameters, the cells of the tumour-bearing animal occupied an intermediate position between the normal and tumour cells.
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