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  • Title: [Food-cobalamin syndrome].
    Author: Serraj K, Vogel T, Federici L, Ciobanu E, Mecili M, Kaltenbach G, Andrès E.
    Journal: Presse Med; 2009 Jan; 38(1):55-62. PubMed ID: 18990540.
    Abstract:
    Food-cobalamin malabsorption is a new well-characterized syndrome. In association with pernicious anemia, it is the leading etiology of cobalamin deficiency in adult, especially in elderly patient. Currently, it is an exclusion diagnosis that requires a well-codified clinical strategy for diagnosis. There are several causes of food-cobalamin malabsorption, mainly gastric disorders and drugs (metformin and anti-acid drugs). Current treatment modality includes oral cobalamin administration with lower doses than in pernicious anemia. Studies are in the way to better characterize the food-cobalamin malabsorption in a clinical practice perspective and to validate the usefulness of oral cobalamin therapy.
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