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Title: [Infantile pyknocytosis: a rare form of neonatal hemolytic anemia. 5 case-studies]. Author: Limme B, Dresse MF, Ketelslegers O, Rigo V, Hoyoux C. Journal: Arch Pediatr; 2008 Dec; 15(12):1765-8. PubMed ID: 18995999. Abstract: UNLABELLED: Infantile pyknocytosis (IP) is a rare hematological entity of newborns. It is a form of hemolytic anemia with unusual red cell morphology: the red blood cells are distorted, irregular, and small with many projections. Spontaneous resolution usually occurs by 4-6months of age. OBSERVATION: We describe the clinical features and biological parameters of 5 cases of IP. The first symptoms were always early jaundice, which required phototherapy. Anemia was severe in all babies and red blood cell transfusion was needed. CONCLUSION: IP is a rare cause of neonatal anemia whose diagnosis is based on a careful peripheral blood smear examination. In our study, anemia was severe and required red blood cell transfusion. Ethnic specificity and familial occurrence are reported in our experience.[Abstract] [Full Text] [Related] [New Search]