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  • Title: A cross-sectional, mono-centric pilot study of insulin resistance in enzyme replacement therapy patients with Gaucher type I without overweight.
    Author: Ucar SK, Coker M, Argin M, Akman S, Kara S, Simsek DG, Darcan S.
    Journal: Mol Genet Metab; 2009 Jan; 96(1):50-1. PubMed ID: 19006678.
    Abstract:
    Insulin resistance have been demonstrated in untreated patients with Gaucher type I disease. It was implied in overweight enzyme replacement therapy (ERT) treated patients with Gaucher type I disease. In present study we investigate whether insulin resistance is presented in fourteen ERT treated patients with Gaucher type I disease and without overweight in comparison to normal subjects. This work illustrates the presence of insulin resistance in non-overweight ERT treated patients with Gaucher type I disease.
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