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Title: MR venography of deep veins: changes with uterine fibroid embolization. Author: Katsumori T, Kasahara T, Tsuchida Y, Nara Y. Journal: Cardiovasc Intervent Radiol; 2009 Mar; 32(2):284-8. PubMed ID: 19011939. Abstract: Deep veins (DVs) can be compressed by a uterus enlarged with fibroids. The purpose of this study was to assess the degree of luminal narrowing of DVs caused by a myomatous uterus, and the change in DV narrowing in women with symptomatic fibroids after embolization using time-of-flight (TOF)-magnetic resonance venography (MRV). Twenty-nine consecutive women with symptomatic uterine fibroids underwent TOF-MRV and pelvic MRI before and 4 months after embolization. Based on the TOF-MRV, we evaluated the luminal narrowing of three DVs, including the inferior vena cava, and the bilateral common and external iliac veins, and divided the findings into three grades. The scores for each DV were added for each patient (lowest, 0; highest, 6). DV scores and symptom severity (SS) scores were compared between the baseline and 4 months after embolization using the paired t-test. The relationship between DV scores and uterine volume was investigated using Pearson's test. DV scores decreased significantly, from 1.52 +/- 1.70 at baseline to 0.93 +/- 1.56 at 4 months after embolization (p = 0.004). The uterine volume decreased from 948 +/- 647 mL at baseline to 617 +/- 417 mL at 4 months after embolization (p < 0.001). DV score correlated with uterine volume (r = 0.856, p < 0.001). SS scores decreased from 54.5 +/- 14.6 at baseline to 26.8 +/- 15.4 at 4 months after embolization (p < 0.001). In conclusion, the degree of luminal narrowing of DVs caused by a uterus with fibroids is correlated with the uterine volume. Uterine artery embolization may induce an improvement of luminal narrowing of DVs due to a reduction of the myomatous uterus volume.[Abstract] [Full Text] [Related] [New Search]