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  • Title: Induced pluripotency of mouse and human somatic cells.
    Author: Maherali N, Hochedlinger K.
    Journal: Cold Spring Harb Symp Quant Biol; 2008; 73():157-62. PubMed ID: 19022751.
    Abstract:
    The identification of transcription factors to induce pluripotency directly in somatic cells has given researchers a unique platform on which to dissect the mechanisms underlying epigenetic reprogramming. In addition, induced pluripotent stem (iPS) cells have enabled the derivation of patient-specific cells for the study and potential treatment of a variety of diseases. Here, we discuss recent discoveries in the reprogramming field including work from our own laboratory.
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