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  • Title: [Preparation and biological safety evaluation of porous n-HA/PA66 composite].
    Author: Li H, Li Y, Yan Y, Zhou G, Wang M, Cheng L.
    Journal: Sheng Wu Yi Xue Gong Cheng Xue Za Zhi; 2008 Oct; 25(5):1126-9. PubMed ID: 19024460.
    Abstract:
    Porous nano-hydroxyapatite/polyamide 66 (n-HA/PA66) composite was developed by injection molding method. Uniformly distributed and interconnected pores with an average size of about 500 microm in matrix were obtained. The evaluation of biological safety of the porous composite including cell cytoxicity test, sensitivity test, pyrogen test, haemolysis test was carried out according to GB/T16886 and GB/T16175. The results showed that the porous n-HA/PA66 composite was of no cytotoxicity, no allergen and pyrogen reactions as well as no hemolytic effect.
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