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  • Title: Quantitative analysis of disulfiram and its metabolites in human blood by gas-liquid chromatography.
    Author: Sauter AM, Wartburg JP.
    Journal: J Chromatogr; 1977 Mar 11; 133(1):167-72. PubMed ID: 190245.
    Abstract:
    A simple method is described that permits the direct quantitative determination of carbon disulphide, free diethyldithiocarbamate and disulphides derived from disulfiram in 1 ml of a patient's blood. It is based on a gas chromatographic determination of carbon disulphide produced from diethyldithiocarbamate and disulfiram using the head-space technique and a flame-photometric detector. The method is compared with a recently described spectrophotometric method.
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