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  • Title: Kinetic tremor and cerebellar ataxia as initial manifestations of Kikuchi-Fujimoto's disease.
    Author: Moon JS, Il Kim G, Koo YH, Kim HS, Kim WC, Kim OJ, Oh SH.
    Journal: J Neurol Sci; 2009 Feb 15; 277(1-2):181-3. PubMed ID: 19027125.
    Abstract:
    Involvement of central nervous system occasionally occurs as a form of aseptic meningitis in Kikuchi-Fujimoto disease (KFD). However, acute cerebellar symptoms are very rare in KFD. We describe a 42 year-old woman presenting kinetic tremor and gait ataxia preceding cervical lymphadenopathy. The diagnosis of KFD was made based on pathology. Lymphocyte-dominant pleocytosis was observed in cerebrospinal fluid. Brain and spinal magnetic resonance imaging showed no structural abnormalities. Acute cerebellar symptoms and cervical lymphadenopathy disappeared spontaneously within 2 months. This case of KFD involved unusual acute cerebellar symptoms. Selective involvement of the cerebellar system by viral or immunologic response may be attributed to acute cerebellar symptoms in KFD.
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