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  • Title: An integrative quantitative model of factors influencing the course of anorexia nervosa over time.
    Author: Yackobovitch-Gavan M, Golan M, Valevski A, Kreitler S, Bachar E, Lieblich A, Mitrani E, Weizman A, Stein D.
    Journal: Int J Eat Disord; 2009 May; 42(4):306-17. PubMed ID: 19040269.
    Abstract:
    OBJECTIVE: To identify factors influencing the course of anorexia nervosa (AN) over time. METHOD: Former female patients with AN (36 remitted and 24 nonremitted) and 31 healthy females responded to standardized interviews and self-rating questionnaires. Remitted patients maintained normal eating, normal weight, and regular menses for the past 12 months. Patients not fulfilling these criteria were considered nonremitted. RESULTS: Using logistic regression, we identified that number of hospitalizations, duration of ambulatory treatment, past vegetarianism, past anxiety, and childhood sexual abuse differentiated remitted from nonremitted patients, predicting nonremission. A similar analysis identified that elevated follow-up vegetarianism and eating-related concerns and lower body mass index (BMI) differentiated remitted from nonremitted patients, contributing to nonremission. Univariate analyses identified that remitted patients had elevated anxiety and eating-related obsessionality compared with the controls, suggesting these variables to potentially predispose to AN. DISCUSSION: Elevated anxiety and eating-related obsessionality may increase the risk for the development of AN and for nonremission.
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