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  • Title: [Brain protein synthesis in awake rats: equilibrium of L-methionine between plasma and direct precursor pool].
    Author: Grange E, Gharib A, Lepetit P, Guillaud J, Sarda N, Bobillier P.
    Journal: C R Acad Sci III; 1991; 312(6):255-60. PubMed ID: 1904301.
    Abstract:
    After 1 hr. of continuous infusion of L-(35S)methionine the specific activities of L-methionine in plasma and tissue-free and tRNA-bound L-methionine in brain were in the same range. This result indicates that, under steady-state conditions, dilution of the precursor pool for protein synthesis (L-methionyl-tRNA) by L-methionine derived from a source other than plasma can be considered as negligible.
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