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  • Title: Synthesis and antimycobacterial activity of selected nitrobenzyloxylated benzotriazoles.
    Author: Augustynowicz-Kopeć E, Zwolska Z, Orzeszko A, Kazimierczuk Z.
    Journal: Acta Pol Pharm; 2008; 65(4):435-9. PubMed ID: 19051584.
    Abstract:
    A series of 1-nitrobenzyloxybenzotriazoles was prepared by the benzylation of the respective halogenosubstituted 1-hydroxybenzotriazoles. The newly obtained compounds were tested against four Mycobacterium strains. Particularly high antimycobacterial activity, comparable with that of isoniazide, was found for 5,6-dichloro- 1-(3,5-dinitrobenzyloxy)- 1H-benzotriazole.
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