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  • Title: Chronic leg ulcers in sickle cell disease: experience in Ibadan, Nigeria.
    Author: Durosinmi MA, Gevao SM, Esan GJ.
    Journal: Afr J Med Med Sci; 1991 Mar; 20(1):11-4. PubMed ID: 1905464.
    Abstract:
    The prevalence of chronic leg ulcers was investigated in 872 adults with sickle cell disease (SCD) (630 HbSS and 242 HbSC) at Ibadan, Nigeria. The incidence was 7.5% in HbSS and 1.7% in HbSC patients. The sex ratio in HbSS was 2:1 in favour of males, and three of the four HbSC were females. Ulcers were sited around the ankles in more than 70% of the patients. The duration of the ulcers varied from less than 1 year to more than 20 years. There was no bias for social class. Response to therapy, including autologous skin graft, was poor.
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