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  • Title: Antibacterial and cytotoxic activity of Kenyan medicinal plants.
    Author: Cyrus WG, Daniel GW, Nanyingi MO, Njonge FK, Mbaria JM.
    Journal: Mem Inst Oswaldo Cruz; 2008 Nov; 103(7):650-2. PubMed ID: 19057813.
    Abstract:
    Seven medicinal plant extracts traditionally used in Kenya, mainly for management of infectious conditions, were chosen and screened for their antibacterial activity against Gram-negative (Pseudomonas aeruginosa and Escherichia coli) and Gram-positive (Bacillus cereus and Staphylococcus aureus) bacteria. Antibacterial activity was tested using the broth dilution method. Harrisonia abyssinica and Terminalia kilimandscharica extracts showed significant activity against Gram+ and Gram- bacteria. The methanolic extracts of T. kilimandscharica bark and H. abyssinica bark and leaves showed minimum inhibitory activity against all tested bacteria, with minimal inhibitory concentrations ranging from 25-150 mg/mL. Ajuga remota and Amaranthus hybridus, which are lethal to brine shrimp nauplii, showed significantly lower antibacterial activity than those that were relatively non-toxic.
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