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  • Title: Antenatal corticosteroid therapy: short-term effects on fetal behaviour and haemodynamics.
    Author: Mulder EJ, de Heus R, Visser GH.
    Journal: Semin Fetal Neonatal Med; 2009 Jun; 14(3):151-6. PubMed ID: 19059817.
    Abstract:
    Antenatal corticosteroid therapy to enhance fetal lung maturity in threatened preterm delivery has a number of non-pulmonary side-effects, both beneficial and undesirable. This review focuses on the short-term (transient) effects of betamethasone and dexamethasone on aspects of fetal circulation and behaviour which are used clinically as markers of fetal well-being. We summarise the effects observed, discuss the proposed underlying mechanisms, and emphasise the consequences for clinical decision-making. Recommendations are given to optimise medical care and to minimise the risk of unwarranted iatrogenic preterm delivery.
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