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  • Title: Congenital Rosai-Dorfman disease presenting with anemia, thrombocytopenia, and hepatomegaly.
    Author: Chow CP, Ho HK, Chan GC, Cheung AN, Ha SY.
    Journal: Pediatr Blood Cancer; 2009 Mar; 52(3):415-7. PubMed ID: 19061211.
    Abstract:
    Rosai-Dorfman disease (RDD) is a rare entity of non-Langerhans cell histiocytoses (non-LCH) which usually presents with bilateral painless cervical lymphadenopathy. We describe a neonate with RDD who presented with anemia, thrombocytopenia and hepatomegaly. He recovered spontaneously with conservative management. This represents an atypical presentation of RDD. Conservative management with close monitoring can be adopted for some with systemic involvement.
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