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  • Title: Folliculotropic mycosis fungoides and a leonine clinical appearance of the face.
    Author: Ito T, Yamamoto T, Matsumoto Y, Wakamatsu J, Kato Y, Tsuboi R.
    Journal: Dermatol Online J; 2008 Sep 15; 14(9):6. PubMed ID: 19061588.
    Abstract:
    A 73-year-old man presented with a two year history of multiple nodules and follicular papules accompanied by slight itching on the face and the forearm. A physical examination showed multiple, soft, erythematous nodules on the forehead, cheek, and jaw, contributing to a generally leonine appearance of the face. Histopathological examination from the forehead revealed dense, massive concentrations of atypical lymphocytes in the dermis, and the forearm showed infiltration of atypical lymphocytes predominantly around the follicles. We diagnosed this condition as folliculotropic cutaneous T cell lymphoma (CTCL). EPOCH therapy was very effective and the lesions of the forehead and forearm showed a decrease in tumor elevation; the histology showed a precipitous decrease in the number of the atypical lymphocytes.
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