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  • Title: Stem cells in the trabecular meshwork: present and future promises.
    Author: Kelley MJ, Rose AY, Keller KE, Hessle H, Samples JR, Acott TS.
    Journal: Exp Eye Res; 2009 Apr; 88(4):747-51. PubMed ID: 19061887.
    Abstract:
    Primary open-angle glaucoma is recognized as a disease of aging, and studies show a relationship between aging and trabecular meshwork (TM) cell density. Human TM cell division occurs primarily in the anterior, non-filtering region. A commonly used glaucoma treatment, laser trabeculoplasty (LTP), triggers and increases cell division, as well as cell migration of these anterior TM cells. These freshly-divided migrating cells repopulate the burned laser sites, suggesting that they are stem cells. Several studies concerning this putative TM stem cell will be discussed.
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