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Title: Distinct cytokine patterns in the aqueous humor of children, adolescents and adults with uveitis. Author: Sijssens KM, Rijkers GT, Rothova A, Stilma JS, de Boer JH. Journal: Ocul Immunol Inflamm; 2008; 16(5):211-6. PubMed ID: 19065415. Abstract: PURPOSE: To determine the immune mediator profile in relation to age in the aqueous humor (AqH) of patients with uveitis. METHODS: AqH of children, adolescents, and adults with uveitis was analyzed for 16 immune mediators. RESULTS: No significant differences were found for IL-8, RANTES, and IP-10. The concentrations of the remaining 13 mediators were significant lower in adults compared with children and adolescents, except for IL-6, which was higher. CONCLUSIONS: Various immune mediators are present in higher concentrations in AqH of children and adolescents with different uveitis entities compared with that of adults, except IL-6, which was higher in adults.[Abstract] [Full Text] [Related] [New Search]