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  • Title: Synthesis and biological activity of some 4-substituted pyrimidines and fused pyrimidines.
    Author: el-Bahaie S, el-Deeb A, Assy MC.
    Journal: Pharmazie; 1991 Jan; 46(1):26-8. PubMed ID: 1907010.
    Abstract:
    The synthesis of 4-beta-cyanoethylthiopyrimidine 2 and 4-chloropyrimidine 8a was chieved from 4-mercapto-5-acetylpyrimidine (1a). Also the synthesis of thienopyrimidine-7,7-dioxide 6, 4-arylaminopyrimidines 9a-e, 4-alkoxypyrimidines 11a, b, pyrimidoquinazoline 10, thienopyrimidines 19a, b and tetrazolopyrimidine 18 was described.
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