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  • Title: ent-Kaurane diterpenoids from Isodon scoparius.
    Author: Zhao Y, Pu JX, Huang SX, Wu YL, Yang LB, Xiao WL, Han QB, Chen GQ, Sun HD.
    Journal: J Nat Prod; 2009 Jan; 72(1):125-9. PubMed ID: 19072209.
    Abstract:
    Nine new ent-kaurane diterpenoids, isoscoparins D-L (1-9), and an artificial product, the acetonide of rabdoloxin A (10), along with 16 known analogues (11-26), were isolated from the leaves of Isodon scoparius. The new structures were determined by 1D and 2D NMR spectroscopic analysis. Selected compounds were evaluated for their cytotoxicity against NB4, A549, PC-3, MCF-7, and SH-SY5Y cell lines.
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