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Title: Antimicrobial activities of jadomycin B and structurally related analogues. Author: Jakeman DL, Bandi S, Graham CL, Reid TR, Wentzell JR, Douglas SE. Journal: Antimicrob Agents Chemother; 2009 Mar; 53(3):1245-7. PubMed ID: 19075054. Abstract: Natural products are leads for new antibiotics as a result of their structural complexity and diversity. We have isolated a series of structurally related polyketide-derived natural products from Streptomyces venezuelae ISP5230. The most active of these jadomycin analogues showed good activity against a variety of staphylococci, including methicillin-resistant Staphylococcus aureus.[Abstract] [Full Text] [Related] [New Search]