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  • Title: Effect of trauma center designation on outcome in patients with severe traumatic brain injury.
    Author: DuBose JJ, Browder T, Inaba K, Teixeira PG, Chan LS, Demetriades D.
    Journal: Arch Surg; 2008 Dec; 143(12):1213-7; discussion 1217. PubMed ID: 19075174.
    Abstract:
    OBJECTIVE: To determine the association of the American College of Surgeons (ACS) designation with outcomes in patients, specifically those with severe traumatic brain injuries. DESIGN: A retrospective review. Logistic regression was performed for mortality, complications, and progression of initial neurologic insult. SETTING: Data from the National Trauma Data Bank. PATIENTS: A total of 16,037 patients with isolated severe head injury (head acute injury score, > or =3 and other body region abbreviated injury score, <3) classified into 2 groups (level 1 and level 2) according to ACS designation. RESULTS: Patients admitted to a level 2 center had higher mortality rates (13.9% vs 9.6%; P < .001), higher rates of complication (15.5% vs 10.6%; P < .001), and higher rates of progression of initial neurologic insult (2.0% vs 1.1%; P < .001). After adjustment for the factors that were different between the 2 groups, admission to a level 2 facility remained an independent predictor of mortality (adjusted odds ratio [OR], 1.57; 95% confidence interval [CI], 1.41-1.75; P < .001), complications (adjusted OR, 1.55; 95% CI, 1.40-1.71; P < .001), and progression of neurologic insult (adjusted OR, 1.78; 95% CI, 1.37-2.31; P < .001). Other independent risk factors for mortality were penetrating mechanism, age of 55 years or older, Injury Severity Score of 20 or higher, Glasgow Coma Scale score of 8 or lower, and hypotension (systolic blood pressure, <90 mm Hg). CONCLUSION: Patients with severe traumatic brain injury treated in ACS-designated level 1 trauma centers have better survival rates and outcomes than those treated in ACS-designated level 2 centers.
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