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  • Title: [Synthesis of Rous sarcoma virus in mammalian embryonal tissue cultures].
    Author: Shevliagin VIa, Chizhevskaia VI.
    Journal: Vopr Onkol; 1976; 22(12):54-7. PubMed ID: 190794.
    Abstract:
    In embryonal cells of mice and hamsters growing in vitro after Rous virus adsorption on them and long before the onset of cell transformation of the virus was detected in thr form closely associated with cells. After exposure of mammalian cells to actinomycin D or after lowering the temperature of their incubation up to +20 degrees C the cell associated virus was not revealed in embryonal cells. This evidences that the de novo synthesis of Rous virus but not the survival of the virus takes palce in the mentioned cells.
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