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  • Title: Quantitation of serum apolipoprotein A-I, A-II, B, C-II, C-III and E in healthy Japanese by turbidimetric immunoassay: reference values, and age- and sex-related differences.
    Author: Noma A, Hata Y, Goto Y.
    Journal: Clin Chim Acta; 1991 Jun 14; 199(2):147-57. PubMed ID: 1908362.
    Abstract:
    Serum apolipoproteins (Apo) A-I, A-II, B, C-II, C-III and E were determined in healthy Japanese subjects (male 1,603, female 1,800, aged 4-95 yr) by the turbidimetric immunoassay, with six kinds of automated instruments, and the commercial reagent kits with standards. There was a high degree of interlaboratory comparability of analytical values among the 15 participating laboratories. The reference values were calculated for adult males and females (male 677, female 467, aged 21-60 yr). Apo A-I and E levels were significantly higher and Apo C-II and C-III were significantly lower in females than in males. Furthermore, serum Apo A-I and A-II tended to decrease, and Apo B to increase with age. Apo C-II, C-III and E tended to decrease after 60 yr of age.
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