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  • Title: Functional evidence that the Ser-195 residue of staphylococcal exfoliative toxin A is essential for biological activity.
    Author: Prévost G, Rifai S, Chaix ML, Piémont Y.
    Journal: Infect Immun; 1991 Sep; 59(9):3337-9. PubMed ID: 1908832.
    Abstract:
    The substitution of the serine 195 residue of staphylococcal exfoliative toxin A by a cysteine residue led to a biologically inactive protein. This result is consistent with the hypothesis that exfoliative toxin A could be a protease or a lipase. However, no protease or lipase activity was detected with the native toxin.
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