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  • Title: Acute and chronic toxicity of organophosphate monocrotophos to Daphnia magna.
    Author: Wang L, Ye W, Zhou S, Lin K, Zhao M, Liu W.
    Journal: J Environ Sci Health B; 2009 Jan; 44(1):38-43. PubMed ID: 19089713.
    Abstract:
    The acute and chronic toxicity of monocrotophos (MCP), the binary joint toxicity of MCP and bifenthrin (BF), and sodium dodecyl benzene sulfonate (SDBS) to Daphnia magna (D. magna) was evaluated. The 24 h-median effective concentration (24 h-EC(50)) and 48 h-median lethal concentration (48 h-LC(50)) of MCP towards D. magna were 161 and 388 micro g/L, respectively. In addition, the lowest-observed effective concentration (LOEC) and non-observed effective concentration (NOEC) of MCP to D. magna were 10 and 5 micro g/L, respectively. Furthermore, the chronic value (ChV) of MCP against D. magna was 7 micro g/L and the acute chronic ratio (ACR) was 55. The number of offspring per female and the intrinsic rate of natural increase (r) were identified as the parameters that were most sensitive to MCP. In addition, toxic unit (TU) analysis was employed to evaluate the joint toxicities. The calculated TU(mix) values of binary equitoxic mixtures of MCP + BF and MCP + SDBS were 1.47 and 1.63, respectively, which suggests that both equitoxic mixtures exert a limited antagonistic effect. The results of this study revealed that the toxic threshold of MCP towards D. magna is higher than its reported highest residue (4 micro g/L) in the ordinary aquatic environment, and that concurrent exposure to BF or SDBS may exert a slight antagonistic effect.
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