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  • Title: Therapy and outcome of orbital primitive neuroectodermal tumor.
    Author: Bakhshi S, Meel R, Naqvi SG, Mohanti BK, Kashyap S, Pushker N, Sen S.
    Journal: Pediatr Blood Cancer; 2009 Apr; 52(4):544-7. PubMed ID: 19090547.
    Abstract:
    Primary orbital primitive neuroectodermal tumor (PNET) is rare with no reported series. We report six cases of orbital PNET treated at a tertiary care oncology center in northern India from 2003 to 2008. None of them had distant metastases. All were treated with neoadjuvant chemotherapy followed by exenteration in two, radiotherapy and adjuvant chemotherapy in five cases. Three out of six achieved complete remission at end of therapy with globe salvage in three and vision in two cases. Chemoradiotherapy may help us to avoid mutilating surgery in large or locally advanced tumors, allowing preservation of vision or the globe.
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