These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Flinderoles A-C: antimalarial bis-indole alkaloids from Flindersia species.
    Author: Fernandez LS, Buchanan MS, Carroll AR, Feng YJ, Quinn RJ, Avery VM.
    Journal: Org Lett; 2009 Jan 15; 11(2):329-32. PubMed ID: 19090698.
    Abstract:
    With the aim of finding new natural product antimalarials, the novel indole alkaloids flinderole A-C were found to have selective antimalarial activities with IC(50) values between 0.15-1.42 microM. Flinderole A was isolated from the Australian plant Flindersia acuminata and flinderoles B and C from the Papua New Guinean plant F. amboinensis. Flinderoles A-C contain an unprecedented rearranged skeleton compared to their related isomers of the borreverine class of compounds.
    [Abstract] [Full Text] [Related] [New Search]