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  • Title: Epstein-Barr virus and human malignancy.
    Author: Ziegler JL, Magrath IT, Gerber P, Levine PH.
    Journal: Ann Intern Med; 1977 Mar; 86(3):323-36. PubMed ID: 190930.
    Abstract:
    The association of the Epstein-Barr virus and two human malignancies, Burkitt's lumphoma and nasopharyngeal carcinoma, is reviewed. Seroepidemiologic, virologic, and immunologic evidence is summarized, and several hypotheses regarding a possible etiologic role for the Epstein-Barr virus in these tumors are presented. With our current state of knowledge we cannot conclude that the Ipstein-Barr virus is oncogenic in man, nor can we yet ascertain the biological and clinical significance of its association with Burkitt's lymphoma and nasopharyngeal carcinoma.
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