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  • Title: Otitis media: prospects for prevention.
    Author: Haggard M.
    Journal: Vaccine; 2008 Dec 23; 26 Suppl 7():G20-4. PubMed ID: 19094934.
    Abstract:
    Alternatives to vaccination for preventing the considerable morbidity of otitis media (OM) are limited. Non-typable Haemophilus influenzae (NTHi) and Streptococcus pneumoniae together account for approximately 80% of OM cases worldwide, so vaccines against these most serious pathogens should materially reduce the burden of OM. Early trial data for a vaccine prototype including NTHi and 11 pneumococcal serotypes, interpreted carefully in relation to other trials, suggest that OM can now be considered a vaccine-preventable disease. Despite differences of scenario according to healthcare and bacteriology circumstances of different countries, a provisional analysis of health-economic precedents and policy considerations favours vaccination.
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