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  • Title: A case of benign intraductal papillary mucinous neoplasm of the pancreas containing two major subtypes.
    Author: Sanada Y, Yoshida K.
    Journal: J Gastrointestin Liver Dis; 2008 Dec; 17(4):457-60. PubMed ID: 19104710.
    Abstract:
    Here we report a case of benign intraductal papillary-mucinous neoplasm (IPMN) of the pancreas containing two major subtypes. A 73-year-old man underwent pancreatoduodenectomy for a cystic mass, 5.0 cm in diameter. Histopathologic examinations revealed that IPMN was composed of gastric-type adenoma and intestinal-type borderline lesion. Marked intraluminal nodular growth was observed in the center of the tumor composed of intestinal-type cells positive for MUC2. Our observations suggest that gastric-type epithelium is a precursor of intestinal-type lesions in the stepwise progression of IPMN.
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