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  • Title: De novo DNA methylation independent establishment of maternal imprint on X chromosome in mouse oocytes.
    Author: Chiba H, Hirasawa R, Kaneda M, Amakawa Y, Li E, Sado T, Sasaki H.
    Journal: Genesis; 2008 Dec; 46(12):spc one. PubMed ID: 19105216.
    Abstract:
    Mouse blastocyst stage embryo stained for histone H3 lysine-27 trimethylation (red) and DNA (blue). H3K27me3 marks the inactive X chromosome. The study by Chiba et al. in this issue suggests that de novo DNA methyltransferases are dispensable for setting the imprint on the maternally-derived X chromsome in growing oocytes. See Chiba et al. in this issue.
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