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  • Title: [An investigation and analysis on an outbreak of acute gastroenteritis caused by genogroup I and II norovirus].
    Author: Han JK, Shen JY, Yao WT, Lwu XQ, Wu XF.
    Journal: Zhonghua Shi Yan He Lin Chuang Bing Du Xue Za Zhi; 2008 Aug; 22(4):263-5. PubMed ID: 19105338.
    Abstract:
    OBJECTIVE: To investigate the cause of an outbreak characterized by diarrhea and vomit in a middle school in Huzhou City. METHODS: Comprehensive analysis was conducted based on field epidemiological study, clinical characteristics of the cases and laboratory test. RESULTS: 578 cases of acute gastroenteritis were found. The attack rate was 23.58%. The most frequently observed clinical symptoms were diarrhea, vomiting, abdominal pain and nausea. Some few had fever. Most cases had slight clinical symptom with a course from 1 to 3 days. The cases were distributed in every class, showing no phenomenon of clustering. Norovirus were detected in 11 out of 15 stool samples by using RT-PCR. 6 were genogroup II norovirus. 3 were genogroup I norovirus. enogroup I and II norovirus were detected at the same time in 2 stool samples (the same student with 2 tests). Case-control study showed that drinking unheated bottled water was risk factor (OR = 2.46, 95% CI = 1.19-5.23), and had a dose response relation with the disease (chi = 24.8 P < 0.01). The epidemic was controlled soon through isolating patients during treatment, providing boiled water, disinfecting and health education. CONCLUSION: This was an infectious diarrhea outbreak caused by norovirus. The suspected transmission ways were drinking unheated bottled water and contact daily.
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