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  • Title: Immunoglobulin allotypes in systemic lupus erythematosus--results of a central European multicenter study. SLE Study Group.
    Author: Hartung K, Coldewey R, Röther E, Pirner K, Specker C, Peter HH, Kalden JR, Lakomek HJ, Deicher H, de Lange GG.
    Journal: Exp Clin Immunogenet; 1991; 8(1):11-5. PubMed ID: 1910857.
    Abstract:
    Immunoglobulin heavy chains (G1m, G2m, G3m, A2m) and kappa light chain (Km) allotype and phenotype frequencies were examined in 323 central European Caucasian patients with systemic lupus erythematosus (SLE). No significant differences were found between the different allotype or phenotype frequencies of the SLE patients and a control group of healthy individuals. Our results indicate that Gm, A2m and Km allotypes do not represent susceptibility factors for SLE in Caucasians.
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