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  • Title: Gene expression: dialing up the frequency.
    Author: Maheshri N.
    Journal: Curr Biol; 2008 Dec 23; 18(24):R1136-9. PubMed ID: 19108770.
    Abstract:
    Cells often respond to external signals by altering their gene expression. The external signaling information is transduced and typically encoded in concentrations of relevant transcription factors. A recent study demonstrates that, by encoding this information in the frequency with which genes 'see' a transcription factor, the expression of hundreds of genes can be modulated in a linearly proportional manner.
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