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  • Title: Comparison of in vitro fertilization versus intracytoplasmic sperm injection in extremely low oocyte retrieval cycles.
    Author: Ou YC, Lan KC, Huang FJ, Kung FT, Lan TH, Chang SY.
    Journal: Fertil Steril; 2010 Jan; 93(1):96-100. PubMed ID: 19108823.
    Abstract:
    OBJECTIVE: To compare the results of IVF and intracytoplasmic sperm injection (ICSI) in extremely low oocyte retrieval cycles. DESIGN: Case-control study. SETTING: An IVF laboratory in a university hospital in Taiwan. PATIENT(S): Between January 2003 and December 2007, infertile couples with one, two, or three oocytes per retrieval were divided into two groups: 56 IVF cycles based on 28 demographic characteristics from the ICSI group. INTERVENTION(S): None. MAIN OUTCOME MEASURE(S): Fertilization rate, cycle cancellation rate, clinical pregnancy rate, and implantation rate per transfer. RESULT(S): The normal fertilization rate was significantly higher after ICSI than after standard IVF (86.4% vs. 69.3%). The cycle cancellation and complete fertilization failure rates were comparable between the two groups. The clinical pregnancy rate per transfer (38.5% vs. 21.6%), implantation rate (23.5% vs. 11.1%), and live birth rate per transfer (30.8% vs. 13.7%) had a favorable trend, but no statistically significant differences, in the ICSI group compared with the IVF group. CONCLUSION(S): A higher normal fertilization rate can be achieved by ICSI in comparison with conventional IVF in extremely low oocyte retrieval cycles.
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