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  • Title: [The specific features of diagnosis of latent small airway obstruction].
    Author: Sukhovskiĭ VS, Strelis AK, Grigor'ev EG, Sukhovskaia VV.
    Journal: Probl Tuberk Bolezn Legk; 2008; (7):39-43. PubMed ID: 19110770.
    Abstract:
    Latent obstruction of the small airway is a preclinical stage of chronic obstructive pulmonary disease (COPD), has no specific signs and it is a risk factor of respiratory failure. Its mechanism is unknown; it is likely to be caused by rearrangement of lung tissue, its increased hydrophicility due to the influence of various endogenous factors, which ultimately causes a change in the mechanical omechanics. The new sensitive functional integral index (the latent small airway obstruction coefficient) has been proposed for timely diagnosis. Body plethysmography was used to comparatively study the health status of 152 women during a gestational period by a special program; of them 66 suffered from COPD. It was found that 26 (16.1%) patients who considered themselves healthy had latent obstruction of the small airway and there was a considerable increase in the number of cases of fetal hypoxic complications.
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