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  • Title: Amniocentesis in twin pregnancies.
    Author: Supadilokluck S, Tongprasert F, Tongsong T, Wanapirak C, Piyamongkol W, Sirichotiyakul S, Srisupundit K.
    Journal: Arch Gynecol Obstet; 2009 Aug; 280(2):207-9. PubMed ID: 19112573.
    Abstract:
    OBJECTIVE: To describe the experiences in diagnostic amniocentesis in twin pregnancies. METHODS: The computerized database and medical records of pregnant women attending Maternal Fetal Medicine Unit of the hospital for diagnostic amniocentesis at 16-20 weeks gestation between January 1992 and December 2006 were retrospectively reviewed. RESULTS: During 15 years of experience, 7,890 amniocenteses at 16-20 weeks gestation were performed for prenatal diagnosis, including 174 procedures in 87 twin pregnancies. The mean gestational age at the time of amniocentesis was 17.13 +/- 3.35 weeks. Preterm birth rate defined as the delivery before 36 gestational weeks was 36.24%. The total fetal loss rate was 5.17%, however, the procedure related fetal loss within 2 weeks after the procedure was 1.15%. CONCLUSION: Based on our limited data and previous studies, we can counsel patients undergoing twin amniocentesis at mid-trimester that the fetal loss rate may be slightly higher than that of singleton amniocentesis.
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