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  • Title: [Value of mfVEP test in pituitary tumors diagnosis].
    Author: Piekarska A, Lubiński W, Gosławski W, Wieliczko W, Syrenicz A, Olszowski T, Karczewicz D.
    Journal: Klin Oczna; 2008; 110(7-9):247-51. PubMed ID: 19112855.
    Abstract:
    PURPOSE: To evaluate the mfVEP test in detection of the optic nerve neuropathy in pituitary tumors. MATERIAL AND METHODS: We examined 30 eyes of 15 patients with confirmed by MRI pituitary tumors (7 patients with macroadenomas and 8 patients with microadenomas). In all patients the routine ophthalmologic examination, multifocal visual evoked potentials (mfVEP) and standard static perimetry (central 24-2 threshold), were performed. The control group consisted of 30 eyes of 15 healthy persons. RESULTS: In 53% (16/30) of eyes manifested changes in static perimetry and/or in mfVEP test. In 13% (4/30) of eyes abnormal static perimetry and mfVEP were simultaneously observed. The only mfVEP abnormalities were the most frequent feature and were observed in 30% (9/30) of eyes. Only abnormal static perimetry results were observed in 10% (3/10) of eyes. In those eyes in related areas of mfVEP recordings the mean peak-to-peak amplitude was significantly reduced compare to the control group. In mfVEP test statistically significant peak-to-peak amplitude reduction was observed in superotemporal quadrants in comparison to the control group (p < 0.009). CONCLUSIONS: MfVEP can be useful test in the optic nerve dysfunction/ neuropathy diagnosis in patients with pituitary tumors.
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