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  • Title: [Leptin, insulin, IGF-1 and bone mass in a group of sedentary adolescent girls].
    Author: El Hage R, Jacob C, Moussa E, Youssef H, Groussard C, Pineau JC, Jaffré C.
    Journal: J Med Liban; 2008; 56(4):220-5. PubMed ID: 19115596.
    Abstract:
    AIM OF THE STUDY: To investigate the relationships between serum leptin, IGF-1, insulin and bone mineral content and density in a group of Lebanese sedentary adolescent girls. METHODS AND RESULTS: Twenty Lebanese sedentary adolescent girls participated in our study. Total body bone mineral content and density were measured by dual-energy X-ray absorptiometry (DEXA). In parallel, fasting leptin, IGF-1 and insulin concentrations were also measured. Serum leptin, IGF-1 and insulin concentrations were not associated with total body bone mineral content (BMC), total body bone mineral density (BMD) or pelvis BMD. CONCLUSION: Serum leptin, IGF-1 and insulin concentrations are not positive predictors of total body bone mineral content or density in this study group.
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