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  • Title: A potent new beta2-adrenoceptor blocking agent.
    Author: Imbs JL, Miesch F, Schwartz J, Velly J, Leclerc G, Mann A, Wermuth CG.
    Journal: Br J Pharmacol; 1977 Jul; 60(3):357-62. PubMed ID: 19116.
    Abstract:
    1 (t-Butyl-amino-3-ol-2-propyl) oximino-9 fluorene is a new beta2-adrenoceptor blocking agent with a pA2 of 9.23+/-0.25 on isolated trachea. 2 It provokes hypertension in normotensive rats and does not prevent arterial hypertension in SHR rats, although it does prevent the renin secretion normally induced by isoprenaline infusion.
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