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Title: Inhibitors of hypoxanthine metabolism in Ehrlich ascites tumor cells in vitro. Author: Smith CM, Zombor G, Henderson JF. Journal: Cancer Treat Rep; 1976 Oct; 60(10):1567-84. PubMed ID: 191189. Abstract: One hundred and sixty-one purine analogs and derivatives were tested for their ability to inhibit ten parameters of purine metabolism in Ehrlich ascites tumor cells incubated in vitro with radioactive hypoxanthine. Sixty-seven compounds were inhibitory against at least one parameter and 30 were inhibitory against two or more.[Abstract] [Full Text] [Related] [New Search]