These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Effects of concanavalin A and neuraminidase on cyclic AMP levels and 14C-1-glucose oxidation in dog thyroid slices.
    Author: Yamashita K, Aiyoshi Y, Oka H, Ogata E.
    Journal: Endocrinol Jpn; 1976 Aug; 23(4):355-8. PubMed ID: 191247.
    Abstract:
    Treatment with concanavalin A at 100 micron/ml or higher concentrations significantly increased 14C-1-glucose oxidation in dog thyroid slices as reported in other tissues. This treatment exerted no effect on tissue cyclic AMP levels. Neuraminidase at the same concentrations also had similar effects on these parameters. Neither concanavalin A nor neuraminidase at the concentrations up to 100 microng/ml had the TSH effect on both tissue cyclic AMP and 14C-1-glucose oxidation. These results indicate that modification of carbohydrate moieties of glycoproteins on the cell surface may cause an increase in glucose metabolism without any critical effect on cyclic AMP system and in the process of TSH response.
    [Abstract] [Full Text] [Related] [New Search]