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  • Title: Effects of penfluridol of dopamine-sensitive adenylate cyclase in corpus striatum and substantia nigra of rats.
    Author: Seeber U, Kuschinsky K.
    Journal: Experientia; 1976 Dec 15; 32(12):1558-9. PubMed ID: 191279.
    Abstract:
    Penfluridol, a neuroleptic with diphenylbutyl piperidine structure, blocked the dopamine-sensitive adenylate cyclase in homogenates of corpus striatum and substantia nigra of rats, probably by a competitive antagonism versus dopamine.
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